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Table 2 In vitro responses to M. tuberculosis antigens in the study group populations.

From: New tools for detecting latent tuberculosis infection: evaluation of RD1-specific long-term response

In vitro

response to:

 

Controls

N (%)

TST+, suspected LTBI

N (%)

Cured TB

N (%)

  

13 (100)

106 (100)

29 (100)

QFT-IT

    
 

Positive N.(%)

0

70 (66.03)

19 (63.3)

 

IFN-γ (IU/ml) median (IQR)

Among all

0 (0-0.1)

2.3 (0-15.1)

1.1 (0.1-4.2)

 

IFN-γ (IU/ml) median (IQR)

Among the positive responders

NA

8.1 (2.4-22.6)

3.8 (1.5-5.0)

RD1 proteins

    
 

Positive N.(%)

0

64 (60.3)

19 (65.5)

 

IFN-γ (IU/ml) median (IQR)

Among all

0 (0-0.2)

1.4 (0.2-8.9)

1.6 (0.4-2.9)

 

IFN-γ (IU/ml) median (IQR)

Among the positive responders

NA

7.6 (2.3-20.3)

2.6 (1.6-6.2)

  1. Footnotes: IQR: inter quartile range; LTBI: latent tuberculosis infection; N: number; QFT-IT: QuantiFERON-TB Gold In-tube; RD: region of difference, TB: tuberculosis.