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Table 3 Changes in log10 levels of IL-8, TNF-α, NE and SLPI from pre-acquisition to acquisition, colonization and exacerbation samples. (p values by comparison to pre-acquisition levels by t test)

From: Moraxella catarrhalisacquisition, airway inflammation and protease-antiprotease balance in chronic obstructive pulmonary disease

  Acquisition-
Mean change (95% CI)
n = 76
Colonization samples only
Mean change (95% CI)
n = 34
Exacerbation samples only
Mean change (95% CI)
n = 42
Change in IL-8 0.39 (0.25-0.53)
(p =< 0.001)
0.23 (0.04-0.42)
(p = 0.015)
0.59 (0.38-0.79)
(p =< 0.001)
Change in TNF-α 0.72 (0.48-0.96)
(p =< 0.001)
0.58 (0.31-0.85)
(p =< 0.001)
0.89 (0.47-1.33)
(p =< 0.001)
Change in Elastase 1.12 (0.79- 1.44)
(p =< 0.001)
0.74 (0.32-1.16)
(p =< 0.001)
1.58 (1.08-2.08)
(p =< 0.001)
Change in SLPI -0.51 (-0.72 to -0.30)
(p =< 0.001)
-0.47 (-0.72- -0.23)
(p =< 0.001)
-0.55 (-0.92- -0.19)
(p = 0.004)