Table 3 Changes in log10 levels of IL-8, TNF-α, NE and SLPI from pre-acquisition to acquisition, colonization and exacerbation samples. (p values by comparison to pre-acquisition levels by t test)
|
Acquisition- Mean change (95% CI) n = 76 |
Colonization samples only Mean change (95% CI) n = 34 |
Exacerbation samples only Mean change (95% CI) n = 42 | |
|---|---|---|---|
| Change in IL-8 |
0.39 (0.25-0.53) (p =< 0.001) |
0.23 (0.04-0.42) (p = 0.015) |
0.59 (0.38-0.79) (p =< 0.001) |
| Change in TNF-α |
0.72 (0.48-0.96) (p =< 0.001) |
0.58 (0.31-0.85) (p =< 0.001) |
0.89 (0.47-1.33) (p =< 0.001) |
| Change in Elastase |
1.12 (0.79- 1.44) (p =< 0.001) |
0.74 (0.32-1.16) (p =< 0.001) |
1.58 (1.08-2.08) (p =< 0.001) |
| Change in SLPI |
-0.51 (-0.72 to -0.30) (p =< 0.001) |
-0.47 (-0.72- -0.23) (p =< 0.001) |
-0.55 (-0.92- -0.19) (p = 0.004) |