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Table 4 Comparison of sensitivities and specificities of a selection of diagnostic real-time PCR assays for GBS (using culture for GBS as gold standard)

From: Evaluation of a novel real-time PCR test based on the ssrAgene for the identification of group B streptococci in vaginal swabs

Reference Assay name Target gene Sensitivity %
(95% CI)
Specificity %
(95% CI)
This study RiboSEQ GBS ssrA 96.4
(90.5 - 98.8)
95.8
(84.6 - 99.3)
Bergeron et al (2000) Not specified cfb 97
(82.5 - 99.8)
100
(94.2 - 100)
Bergseng et al (2007) Not specified sip 97
(90 - 99)
99
(97 - 100)
Davies et al (2004) IDI-Strep B cfb 94
(90.1 - 97.8)
95.9
(94.3 - 97.4)
Gavino and Wang (2007) GeneXpert GBS cfb 95.8
(76.9 - 99.8)
64.5
(45.4 - 80.2)
Uhl et al (2005) LightCycler Strep B ptsI 100
(88.8 - 100)
96.9
(92.2 - 99.1)