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Table 3 Sensitivity, specificity, predictive values (PPV, NPV) and likelihood ratios +LR, -LR) for the RiboSEQ GBS test and the BD GeneOhmâ„¢ StrepB Assay

From: Evaluation of a novel real-time PCR test based on the ssrAgene for the identification of group B streptococci in vaginal swabs

  

RiboSEQGBS test

BD GeneOhmâ„¢ StrepB Assay

  

Positive

Negative

Positive

Negative

Culture a

Positive

107

4

105

6

 

Negative

2

46

5

43

 

Sensitivity

96.4%

94.6%

 

95% CI

(90.5 - 98.8%)

(88.1 - 97.8%)

 

Specificity

95.8%

89.6%

 

95% CI

(84.6 - 99.3%)

(76.6 - 96.1%)

 

PPV b

98.2%

95.5%

 

95% CI

(92.9 - 99.7%)

(89.2 - 98.3%)

 

NPV b

92%

87.8%

 

95% CI

(79.9 - 97.4%)

(74.5 - 94.9%)

 

+LR b

23.1

9.1

 

95% CI

(5.9 - 89.9)

(3.9 - 20.8)

 

-LR b

0.04

0.06

 

95% CI

(0.01 - 0.1)

(0.03 - 0.13)

  1. Calculated using programme available at http://faculty.vassar.edu/lowry/clin1.html
  2. a using culture as the gold standard (n = 159)
  3. b sample population comprised of random (n = 39) and non-random (n = 120) specimens