Skip to main content

Table 1 Patient and VNTR Profiles whose M. tuberculosis Indicated M-strains

From: Transmission of Specific Genotype Streptomycin Resistant Strains of Mycobacterium tuberculosisin the Tokyo Metropolitan Area in Japan

No. M-strain Type (*1) Year Patient Registed TB diagnosis
(*2)
sex (*3) Age (years old) Internet-café use (*4) Homeless (*5) Drug Resistance (*6) VNTR profiles (*7)
1 M5 2004 univ M 22 No No SM 223315173533-42 5 3-884443 4 -4337
2 M5 2004 univ M 22 No No SM 223315173533-42 5 3-884443 3 -4337
3 M5 2004 univ M 22 No No SM 223315173533-42 5 3-884443 4 -4337
4 M5 2004 univ M 22 Yes No SM 223315173533-42 5 3-884443 4 -4337
5 M5 2004 univ F 21 No No SM 223315173533-42 5 3-884443 3 -4337
6 M5 2004 univ M 22 No No SM 223315173533-42 5 3-884443 4 -4337
7 M5 2004 univ M 22 No No SM 223315173533-42 5 3-884443 3 -4337
8 M5 2004 univ M 22 No No SM 223315173533-42 5 3-884443 3 -4337
9 M5 2004 univ M 22 No No SM & INH 223315173533-42 5 3-884443 4 -4337
10 M5 2004 univ M 22 No No SM & INH 223315173533-42 5 3-884443 4 -4337
11 M5 2004 univ M 22 No No SM 223315173533-42 5 3-88 2443 4 -4337
12 M5 2005 univ F unknown No No SM 223315173533-42 5 3-884443 4 -4337
13 M5 2005 univ M 22 No No SM 223315173533-42 5 3-884443 4 -4337
14 M5 2005 univ M 24 No No SM 223315173533-42 5 3-884443 3 -4337
15 M5 2005 univ M 21 No No SM 223315173533-42 5 3-884443 4 -4337
16 M5 2005 univ M 22 No No SM 223315173533-42 5 3-884443 4 -4337
17 M5 2005 univ M 23 No No SM 223315173533-42 5 3-884443 3 -4337
18 M5 2005 univ M 22 No No SM 223315173533-42 5 3-884443 4 -4337
19 M5 2006 s M 58 No Yes SM 223315173533-42 5 3-884443 3 -4337
20 M5 2007 s M 39 Yes Yes SM 223315173533-42 5 3-884443 3 -4337
21 M4 2003 s M 59 No No SM 223315173533-42 4 3-884443 3 -4337
22 M4 2004 univ M 22 Yes No SM 223315173533-42 4 3-884443 3 -4337
23 M4 2004 univ M 24 No No SM 223315173533-42 4 3-884443 3 -4337
24 M4 2004 Ob M 24 No No SM 223315173533-42 4 3-884443 3 -4337
25 M4 2004 Ob M 35 No No SM 223315173533-42 4 3-884443 3 -4337
26 M4 2004 ka M 49 No Yes SM 223315173533-42 4 3-884443 3 -4337
27 M4 2004 ka M 31 No No SM 223315173533-42 4 3-884443 3 -4337
28 M4 2004 ka M 41 No No SM 223315173533-42 4 3-884443 3 -4337
29 M4 2004 s M 65 Yes Yes SM 223315173533-42 4 3-884443 3 -4337
30 M4 2005 Ob(ka) M 47 Yes Yes SM 223315173533-42 4 3-884443 3 -4337
31 M4 2005 Ob(s) M 28 Yes No SM 223315173533-42 4 3-884443 3 -4337
32 M4 2005 Ob M 31 Yes Yes SM 223315173533-42 4 3-884443 3 -4337
33 M4 2005 Ob M 25 Yes Yes SM 223315173533-42 4 3-884443 3 -4337
34 M4 2005 ka M 30 No No SM 223315173533-42 4 3-884443 3 -4337
35 M4 2005 ka F 56 No No SM 223315173533-42 4 3-884443 3 -4337
36 M4 2005 ka M 45 Yes Yes SM 223315173533-42 4 3-884443 3 -4337
37 M4 2006 ka M 67 No No SM 223315173533-42 4 3-884443 3 -4337
38 M4 2006 ka M 58 No No SM 223315173533-42 4 3-884443 3 -4337
39 M4 2006 s F 33 No No SM 223315173533-42 4 3-884443 3 -4337
40 M4 2007 ka M 46 No No SM 223315173533-42 4 3-884443 3 -4337
41 M4 2007 ka M 54 No No SM 223315173533-42 4 3-884443 3 -4337
42 M4 2007 ka M 44 No No SM 223315173533-42 4 3-684443 3 -4337
43 M4 2007 ka F 39 No No SM 223315173533-42 4 3-884443 3 -4337
44 M4 2007 ka M 55 No No SM 223315173533-42 4 3-884443 3 -4337
45 M4 2007 s M 50 Yes Yes SM 223315173533-42 4 3-884443 3 -4337
46 M4 2007 s M 45 No Yes SM 223315173533-42 4 3-884443 3 -4337
  1. *1: "M4" indicates the M4-substrain with four tandem repeat copies at the ETR C locus. "M5" indicates the M5-substrain with five tandem repeat copies at the ETR C locus.
  2. *2: "univ" indicates a TB patient detected through the contact investigation related to the tuberculosis outbreak at the university campus mentioned in the text.
  3. "Ob" indicates a TB patient detected through contact investigations related to tuberculosis outbreak incidents other than the one at the university campus mentioned above.
  4. "s" indicates a TB patient detected through the population-based DNA fingerprinting surveillance of M. tuberculosis in Shinjuku City.
  5. "ka" indicates a TB patient detected through the hospital-based DNA fingerprinting surveillance of M. tuberculosis in Kawasaki City.
  6. *3: "M" indicates male and "F" indicates female
  7. *4: "Yes" indicates a TB patient who claimed to have a past history of the use of some internet cafés in the TMA within the past two years.
  8. *5: A homeless person is defined as a person whose legal address is unknown or unstable at least within the past two years.
  9. *6: Anti-tuberculosis agents the isolated M. tuberculosis indicated resistance. "SM" stands for Streptomycin, "INH" stands for Isoniazid.
  10. *7: The 12 digits at the first part of the VNTR profile indicate the tandem repeat copy numbers according to the following loci set order: MIRU2, MIRU4, MIRU10, MIRU16, MIRU20, MIRU23, MIRU24, MIRU26, MIRU27, MIRU31, MIRU39, MIRU40 (Reference 5).
  11. The 4 digits at the second part of the VNTR profile indicate the tandem repeat copy numbers according to the following loci set order: ETR A, ETR B, ETR C, ETR F (Reference 6).
  12. The 7 digits at the third part of the VNTR profile indicate the tandem repeat copy numbers according to the following loci set order: QUB11b, QUB26, Mtub04, Mtub21, Mtub30, Mtub39, VNTR4156 (Reference 7).
  13. The 4 digits at the last part of the VNTR profile indicate the tandem repeat copy numbers according to the following loci set order: QUB15, Mtub24, VNTR2372, VNTR3336 (Reference 8).