Table 3 Frequencies of HLA class II alleles in leprosy subgroups and control group
Alleles | Lepromatous | Controls | |||||
|---|---|---|---|---|---|---|---|
(N = 63) | (N = 217) | P | OR | CI 95% | |||
n | % | n | % | ||||
DRB1*04 | 4 | 3.2 | 42 | 9.7 | 0.0165 | 0.31 | 0.11–0.87 |
DRB1*16 | 10 | 7.9 | 14 | 3.2 | 0.0405 | 2.59 | 1.12–5.97 |
DRB1*1602 | 6 | 4.8 | 5 | 1.2 | 0.0197 | 4.29 | 1.29–14.30 |
N = 40 | N = 178 | ||||||
DQA1*03 | 3 | 3.8 | 43 | 11.5 | 0.0184 | 0.25 | 0.07–0.87 |
DQA1*05 | 26 | 32.5 | 78 | 20.9 | 0.0220 | 2.38 | 1.17–4.86 |
N = 40 | N = 184 | ||||||
DQB1*02 | 22 | 27.5 | 59 | 15.8 | 0.0103 | 2.59 | 1.29–5.19 |
Borderline | Controls | ||||||
(N = 44) | (N = 217) | ||||||
DRB1*09 | 6 | 6.8 | 7 | 1.6 | 0.0112 | 4.74 | 1.51–14.87 |
DRB1*16 | 8 | 9.0 | 14 | 3.2 | 0.0175 | 3.22 | 1.26–8.23 |
DRB1*1601 | 8 | 9.0 | 8 | 1.8 | 0.0016* | 5.81 | 2.05–16.46 |
N = 30 | N = 178 | ||||||
DQA1*04 | 1 | 1.7 | 34 | 9.1 | 0.0337 | 0.15 | 0.02–1.11 |
Tuberculoid | Controls | ||||||
(N = 45) | (N = 217) | ||||||
DRB1*1602 | 4 | 4.4 | 5 | 1.1 | 0.0498 | 4.14 | 1.07–16.06 |
N = 24 | N = 178 | ||||||
DQA1*02 | 0 | 0 | 28 | 7.5 | 0.0298 | 0.23 | 0.03–1.8 |
DQA1*05 | 18 | 37.5 | 78 | 20.9 | 0.0046 | 3.85 | 1.46–10.15 |