Figure 3

CJD profiles of MRI and EEG from probable CJD patients. (A) Brain MRIs of Cases 1, 2, and 3 with PRNP polymorphisms. The two images at the top and bottom left are of Case 1 with the D178N-129M mutation; the two images at center are of Case 2 with the E200K-129MV mutation; and the two images at top and bottom right are of Case 3 with M232R mutation. The top three are DWI images and the bottom three are T2-FLAIR images. The white arrow indicates a lesion with a high signal. (B) EEG of Case 2 (left panel) and Case 3 (right panel). The EEG of Case 1 was normal (data not shown).