Skip to main content

Table 3 Survival following HIV diagnosis and the estimated hazard ratio of variables by year of diagnosis

From: Improvement in survival among HIV-infected individuals in the Republic of Korea: Need for an early HIV diagnosis

  

1985–1990

1991–1996

1997–2002

2003–2007

Variables

Cox's Regression

Case No.(%)

HR (95%CI)

P-value

Case No.(%)

HR (95%CI)

P-value

Case No.(%)

HR(95%CI)

P-value

Case No.(%)

HR

Gender

            

   Men

Unadjusted

105

(85)

2.2(1.7–2.9)

< .0001

440

(89)

1.5(1.2–1.9)

< .0001

1230

(89)

1.3(1.1–1.6)

0.001

3082

(93)

1

 

Adjusted

 

4.3(3.2–5.9)

< .0001

 

3.0(2.4–3.7)

< .0001

 

1.3(1.1–1.5)

0.0022

 

1

   Women

Unadjusted

19

(15)

2.4(1.0–6.0)

0.0513

57

(11)

2.3(1.1–4.6)

0.0209

158

(11)

1.5(0.8–2.8)

0.2444

232

(7)

1

 

Adjusted

 

4.3(1.6–11.4)

0.0037

 

4.2(2.0–9.0)

0.0001

 

1.6(0.9–3.1)

0.1402

 

1

Age

            

   ≤ 29

Unadjusted

60

(48)

3.7(2.0–7.0)

< .0001

198

(40)

2.0(1.1–3.6)

0.0188

339

(24)

1.4(0.8–2.5)

0.2553

766

(23)

1

 

Adjusted

 

4.8(2.5–9.3)

< .0001

 

2.9(1.6–5.3)

0.0007

 

1.5(0.9–2.8)

0.1514

 

1

   30–39

Unadjusted

40

(32)

3.5(2.2–5.7)

< .0001

184

(37)

2.6(1.8–3.7)

< .0001

472

(34)

1.7(1.2–2.3)

0.0016

1062

(32)

1

 

Adjusted

 

6.6(3.9–11.1)

< .0001

 

4.1(2.8–6.0)

< .0001

 

1.7(1.2–2.3)

0.0016

 

1

   40–49

Unadjusted

18

(15)

2.3(1.3–4.1)

0.0065

76

(15)

2.5(1.7–3.6)

< .0001

323

(23)

1.4(1.1–1.9)

0.0181

803

(24)

1

 

Adjusted

 

2.4(1.3–4.4)

0.0072

 

3.2(2.2–4.7)

< .0001

 

1.4(1.0–1.9)

0.0293

 

1

   ≥ 50

Unadjusted

6

(5)

3.7(1.6–8.3)

0.0019

39

(8)

1.5(1.0–2.4)

0.0755

254

(18)

1.2(0.9–1.5)

0.2709

683

(21)

1

 

Adjusted

 

5.1(2.2–12.0)

0.0002

 

2.7(1.7–4.4)

< .0001

 

1.1(0.8–1.5)

0.4569

 

1

Screening site

            

   Public institution

Unadjusted

86

(69)

3.5(2.2–5.8)

< .0001

295

(59)

2.4(1.6–3.8)

0.0001

388

(28)

1.8(1.1–2.8)

0.0148

621

(19)

1

 

Adjusted

 

4.5(2.7–7.4)

< .0001

 

3.1(2.0–4.9)

< .0001

 

1.7(1.1–2.7)

0.0248

 

1

   Hospital

Unadjusted

17

(14)

3.7(2.1–6.5)

< .0001

121

(24)

2.8(2.1–3.7)

< .0001

857

(62)

1.6(1.3–1.8)

< .0001

2451

(74)

1

 

Adjusted

 

4.0(2.3–7.1)

< .0001

 

3.5(2.7–4.7)

< .0001

 

1.4(1.2–1.7)

0.0003

 

1

   Blood center

Unadjusted

21

(17)

2.5(0.5–11.3)

0.2406

81

(16)

1.5(0.3–6.1)

0.6111

143

(10)

0.7(0.2–3.1)

0.6275

242

(7)

1

 

Adjusted

 

4.9(1.0–25.1)

0.0546

 

2.2(0.5–9.8)

0.3165

 

0.9(0.2–4.1)

0.8896

 

1

CD4+ T-cell counts*

            

   <200

Unadjusted

10

(20)

1.6(1.0–2.5)

0.0707

63

(18)

1.9(1.5–2.5)

< .0001

313

(35)

1.2(1.0–1.5)

0.0221

783

(37)

1

 

Adjusted

 

2.7(1.6–4.4)

0.0001

 

2.8(2.1–3.7)

< .0001

 

1.3(1.1–1.6)

0.0063

 

1

   200–349

Unadjusted

3

(6)

5.0(2.2–11.7)

0.0002

71

(21)

2.7(1.4–5.4)

0.0035

212

(24)

1.1(0.6–2.1)

0.7649

582

(28)

1

 

Adjusted

 

6.3(2.6–15.0)

< .0001

 

2.7(1.4–5.5)

0.005

 

1.0(0.5–2.0)

0.9749

 

1

   350–499

Unadjusted

13

(25)

1.9(0.7–5.3)

0.2351

90

(26)

1.0(0.4–2.7)

0.9422

172

(19)

0.8(0.3–2.1)

0.7298

392

(19)

1

 

Adjusted

 

2.6(0.9–7.7)

0.081

 

1.1(0.4–3.0)

0.8152

 

0.9(0.3–2.2)

0.7546

 

1

   ≥ 500

Unadjusted

25

(49)

3.4(1.4–8.4)

0.0076

120

(35)

2.1(0.9–4.9)

0.1056

192

(22)

1.3(0.5–3.1)

0.6153

328

(16)

1

 

Adjusted

 

3.5(1.3–9.0)

0.0117

 

2.2(0.9–5.4)

0.0966

 

1.3(0.5–3.1)

0.6118

 

1

  1. CI: Confidence Interval, HR: Hazard Ratio
  2. *Individuals were classified by initial CD4+ T-cell counts within 6 months of HIV diagnosis, including individuals who died from AIDS within 6 months of HIV diagnosis. Individuals without CD4+ T-cell counts or CD4+ T-cell counts measured greater than 6 months of HIV diagnosis were designated as the "missing group" (data not shown).
Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us