Improvement in survival among HIV-infected individuals in the Republic of Korea: Need for an early HIV diagnosis

BMC Infectious Diseases

Table 2 Proportion of survival following HIV diagnosis and the estimated hazard ratios for variables

			Unadjusted		Adjusted
Variable	No. of cases	Proportion surviving after 10 years (95% CI)	Hazard Ratio (95% CI)	p-value	Hazard Ratio (95% CI)	p-value
Gender
Men	4,861	67%(64–69)	1.31(1.04,1.65)	0.0211	1.37(0.09,1.73)	0.0082
Women	462	73%(66–78)	1.00	-	1.00	-
Age
≤ 29	1,363	81%(77–84)	1.00	-	1.00	-
30–39	1,758	71%(66–74)	1.80(1.47,2.20)	< .0001	1.46(1.19,1.80)	0.0003
40–49	1,220	56%(50–63)	2.94(2.40,3.61)	< .0001	2.10(1.70,2.60)	< .0001
≥ 50	982	49%(41–57)	4.37(3.56,5.35)	< .0001	3.08(2.48,3.83)	< .0001
Screening site
Public institution	1,394	68%(64–71)	1.00	-	1.00	-
Hospital	3,448	68%(64–72)	1.47(1.27,1.70)	< .0001	1.50(1.27,1.76)	< .0001
Blood center	481	85%(78–89)	0.39(0.28,0.55)	< .0001	0.62(0.44,0.88)	0.0067
Year of diagnosis
1985–1990	124	56%(46–64)	2.15(1.65,2.80)	< .0001	5.03(3.77,6.71)	< .0001
1991–1996	497	62%(57–66)	1.57(1.29,1.90)	< .0001	3.48(2.81,4.30)	< .0001
1997–2002	1,338	70%(66–73)	1.31(1.11,1.54)	0.0011	1.42(1.21,1.68)	< .0001
2003–2007	3,314	-	1.00	-	1.00	-
CD4+ T-cell counts*
<200	1,169	46%(41–51)	5.51(4.47,6.78)	< .0001	5.10(4.11,6.33)	< .0001
200–349	868	70%(63–75)	1.06(0.81,1.38)	0.6872	1.13(0.86,1.47)	0.3865
350–499	667	80%(74–84)	0.77(1.81,2.92)	0.0757	0.80(0.60,1.06)	0.1223
≥500	665	80%(75–84)	1.00	-	1.00	-

CI: Confidence Interval
*Individuals were classified by initial CD4+ T-cell counts within 6 months of HIV diagnosis, including individuals who died from AIDS within 6 months of HIV diagnosis. Individuals without CD4+ T-cell counts or CD4+ T-cell counts measured greater than 6 months of HIV diagnosis were designated as the "missing group" (data not shown).

ISSN: 1471-2334