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Figure 1 | BMC Infectious Diseases

Figure 1

From: Epidemiologic natural history and clinical management of Human Papillomavirus (HPV) Disease: a critical and systematic review of the literature in the development of an HPV dynamic transmission model

Figure 1

Overview of epidemiologic structure of multi-HPV type model. HPV infection may progress to either genital warts or cervical disease, with regression possible for HPV infection, CIN grades 1–3 and genital warts. Only cervical cancer confers an added risk of mortality, as depicted in the figure. However, in the full model (not shown for simplicity) all individuals face an underlying age and sex-specific mortality rate due to non-cervical cancer-related causes. CIN = Cervical Intraepithelial Neoplasia; HPV = Human Papillomavirus.

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