Characteristics | All patients n = 255 | Patients with at least one drug resistance mutation (NRTI, NNRTI, PI)d n = 15 | Patients with wild type virus n = 240 | P-value e | OR (95% CI)f |
---|---|---|---|---|---|
Italian a N (%) | 188 (75.5) | 14 (93.3) | 174 (74.3) | 0.13 | 4.8 (0.6–37.5) |
Male a N (%) | 193 (77.5) | 14 (93.3) | 179 (76.5) | 0.13 | 4.8 (0.6–37.5) |
Median age (years) (IQR) a | 37 (31–43) | 38 (34–46) | 37 (30–43) | 0.35 | |
Risk exposure N (%) | |||||
Heterosexual | 108 (47.6) | 2 (13.3) | 106 (50.0) | 0.01 | 0.15 (0.03–0.70) |
Homosexual | 110 (48.6) | 13 (86.7) | 97 (45.8) | 0.008 | 7.7 (1.7–35.0) |
Intravenous drug use | 9 (4.0) | 0 (0.0) | 9 (4.2) | 1.00 | 0.0 (0.0–6.1) |
Unknown, no. | 28 | 0 | 28 | ||
Viral Load, Median (IQR), (log copies/ml) | 4.9 (4.3–5.4) | 4.5 (4.3–5.2) | 4.9 (4.3–5.4) | 0.40 | |
CD4+ count, Median (IQR), cell/mm3 | 372 (171–517) | 336 (132–450) | 385 (194–527) | 0.50 | |
Co-infection N (%) | |||||
HBV | 33 (13.3) | 0 (0.0) | 33 (13.7) | 0.23 | 0.0 (0.0–1.6) |
HCV | 26 (10.4) | 0 (0.0) | 26 (10.8) | 0.38 | 0.0 (0.0–2.2) |
HIV-1 subtypes | |||||
Subtype B | 213 (83.5) | 15 (100) | 198 (82.5) | 0.99 | inf (2.2-inf) |
Other Subtypes | 42 (16.5) | 0 (0.0) | 42 (17.5) | 0.99 | 0.0 (0.0–1.2) |
Infectious status | |||||
Long-standing Infection, > 6 months b | 197 (77.2) | 13 (86.7) | 184 (76.7) | 0.38 | 2.0 (0.4–9.0) |
Recent Infection, ≤ 6 months c | 58 (22.7) | 2 (13.3) | 56 (23.3) | 0.38 | 0.50 (0.11–2.3) |