Tularemia induces different biochemical responses in BALB/c mice and common voles

BMC Infectious Diseases

Table 2 Development of CREA, UREA and CK in the course of tularemia.

Groups	CREA		UREA		CK
	M. musculus	M. arvalis	M. musculus	M. arvalis	M. musculus	M. arvalis
0	47.50 ± 3.89	41.33 ± 12.89	7.65 ± 0.98	6.84 ± 1.75	12.57 ± 6.13	14.76 ± 10.33
1	71.25 ± 6.11**	66.50 ± 24.06**	9.30 ± 2.67	6.87 ± 1.35	10.10 ± 3.18	11.87 ± 7.23
2	40.71 ± 12.95	33.33 ± 8.26	6.34 ± 1.65	5.40 ± 2.04	10.48 ± 7.45	12.12 ± 6.37
3	30.57 ± 2.97**	49.62 ± 14.31	12.57 ± 6.38	7.15 ± 3.29	18.42 ± 16.54	14.98 ± 9.98
4	30.22 ± 3.19**	41.50 ± 10.47	9.71 ± 6.92	7.86 ± 7.75	18.23 ± 13.38	15.04 ± 6.11
5	41.66 ± 1.80	47.60 ± 13.80	12.73 ± 6.97	4.46 ± 1.27	18.85 ± 6.17	16.63 ± 6.21
6		42.50 ± 1.58		8.15 ± 0.58		11.74 ± 1.53

CREA = creatinine (μmol/l), UREA = urea (mmol/l), CK = creatine kinase (μkat/l), M. musculus = BALB/c mice, M. arvalis = Microtus arvalis, 0 = control group, 1 to 6 = groups of animals sampled on days 1 to 6 post-infection, n = 10 in each group, * = p < 0.05, ** = p < 0.01 when compared against control group. Values represent mean ± SD.

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