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Table 2 Logistic models with logit links for different clinical manifestations and laboratorial assays during dengue fever based on cytokine production.

From: Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity

Severity1 Yes = 39, No = 20 3

Coefficient

Error

P value (significance)4

OR2(CI 95% range)

Intercept

10.855

4.150

0.0089**

-

Log (MIP-1β +1e-4) -

1.712

0.705

0.0153*

0.181(0.045–0.72)

Log (IFN-γ +1e-4)

0.130

0.046

0.0046**

1.138 (1.041–1.245)

Platelet counts 50.000/mm 3 Yes = 18 No = 40

Coefficient

Error

P value (significance)

OR (CI 95% range)

Intercept

0.940

0.943

0.3187

-

MIP-1β

-0.010

0.023

0.0057**

0.990 (0.983–0.997)

IL-1β

0.056

0.023

0.0123*

1.058 (1.012–1.106)

TNF-α

-0.022

0.008

0.0100*

0.978(0.962–0.995)

MCP-1

0.002

0.001

0.0437*

1.002 (1.0001–1.0036)

Hypotension Yes = 24 No = 35

Coefficient

Error

P value (significance)

OR (CI 95% range)

Intercept

0.357

0.742

0.6302

-

IL-1β

0.075

0.038

0.0454*

0.928 (0.862–0.999)

IL-12

0.005

0.012

0.6516

1.006 (0.982–1.030)

IL-13

-0.013

0.014

0.3519

0.987 (0.960–1.015)

MIP-1β

-0.004

0.002

0.0807

0.996 (0.992–1.000)

MCP-1

0.001

0.0007

0.2065

1.001 (0.9995–1.002)

GM-CSF

0.0043

0.0017

0.0214*

1.004 (1.001–1.007)

  1. 1Models were chosen according to their best Akaike information criterion (AIC). In this model we used MIP-1β and IFN-γ log values in order to obtain a small AIC.
  2. 2 OD, odds ratio; CI, confidence interval.
  3. 3Number of patients.
  4. 4 * P < 0.05, ** P < 0.01 and *** P < 0.001.