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Table 2 Logistic models with logit links for different clinical manifestations and laboratorial assays during dengue fever based on cytokine production.

From: Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity

Severity1 Yes = 39, No = 20 3 Coefficient Error P value (significance)4 OR2(CI 95% range)
Intercept 10.855 4.150 0.0089** -
Log (MIP-1β +1e-4) - 1.712 0.705 0.0153* 0.181(0.045–0.72)
Log (IFN-γ +1e-4) 0.130 0.046 0.0046** 1.138 (1.041–1.245)
Platelet counts 50.000/mm 3 Yes = 18 No = 40 Coefficient Error P value (significance) OR (CI 95% range)
Intercept 0.940 0.943 0.3187 -
MIP-1β -0.010 0.023 0.0057** 0.990 (0.983–0.997)
IL-1β 0.056 0.023 0.0123* 1.058 (1.012–1.106)
TNF-α -0.022 0.008 0.0100* 0.978(0.962–0.995)
MCP-1 0.002 0.001 0.0437* 1.002 (1.0001–1.0036)
Hypotension Yes = 24 No = 35 Coefficient Error P value (significance) OR (CI 95% range)
Intercept 0.357 0.742 0.6302 -
IL-1β 0.075 0.038 0.0454* 0.928 (0.862–0.999)
IL-12 0.005 0.012 0.6516 1.006 (0.982–1.030)
IL-13 -0.013 0.014 0.3519 0.987 (0.960–1.015)
MIP-1β -0.004 0.002 0.0807 0.996 (0.992–1.000)
MCP-1 0.001 0.0007 0.2065 1.001 (0.9995–1.002)
GM-CSF 0.0043 0.0017 0.0214* 1.004 (1.001–1.007)
  1. 1Models were chosen according to their best Akaike information criterion (AIC). In this model we used MIP-1β and IFN-γ log values in order to obtain a small AIC.
  2. 2 OD, odds ratio; CI, confidence interval.
  3. 3Number of patients.
  4. 4 * P < 0.05, ** P < 0.01 and *** P < 0.001.