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Figure 6 | BMC Infectious Diseases

Figure 6

From: Brain injury-associated biomarkers of TGF-beta1, S100B, GFAP, NF-L, tTG, AbetaPP, and tau were concomitantly enhanced and the UPS was impaired during acute brain injury caused by Toxocara canisin mice

Figure 6

Expression of GFAP and NF-L in the brains of T. canis infected mice. (A) Protein levels of GFAP and NF-L in the brains of infected mice from 3 dpi to 8 wpi assessed by Western blotting. (B) Relative times were generated as described in Fig. 5B. The error bars indicate the S.D. and the superscript indicates significant differences from the control; # P < 0.001. (C) Expression levels of GFAP and NF-L in the brains of infected mice from 3 dpi to 8 wpi were assessed by RT-PCR. (D) The relative amounts of GFAP and NF-L mRNA were calculated based on the optical density relative to that of the GAPDH. The error bars indicate the S.D. and the superscripts represent significant differences from the control; + P < 0.01, # P < 0.001. Three to eight mice per group were examined.

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