Skip to main content

Table 3 False positive cases.

From: Development and optimization of quantitative PCR for the diagnosis of invasive aspergillosis with bronchoalveolar lavage fluid

Pt.

AspergillusDNA (fg/pellet)

BAL Culture

Clinical Diagnosis

Computed tomography scan results and other clinical information

1

5230

negative

DAH

Organizing pneumonia on lung biopsy with pulmonary hemorrhage; treated with ambisome empirically; No IPA at autopsy

2

230

negative

BOOP

Bilateral patchy opacities; no mould active antifungal therapy given

3

60

negative

Unknown

Nodular right middle lobe infiltrate treated with levofloxacin; exposure to hay

4

340

negative

IPA

Multiple bilateral nodules; treated as IPA with voriconazole + caspofungin

5

320

negative

DAH

Bilateral geographic grounds glass opacities; treated with caspofungin

6

80

negative

BOOP

Numerous bilateral ground glass opacities; treated with prednisone but no antifungal therapy

7

170

negative

Influenza pneumonia/PCP

Left lung infiltrates; no antifungal therapy except for Pneumocystis

  1. Additional information about false positive (FP) cases as identified by qPCR. Pt.: patient; BOOP: Bronchiolitis obliterans with organizing pneumonia; DAH: Diffuse alveolar hemorrhage; PCP: Pneumocystis pneumonia.