Figure 1From: Differential effects of antibiotics in combination with G-CSF on survival and polymorphonuclear granulocyte cell functions in septic rats Kaplan-Meier 120 h survival analysis of septic rats from two independent CMRTs. Each group included n = 18 rats. A) Rats with coamoxiclav prophylaxis (10 mg/kg), coamoxiclav plus G-CSF prophylaxis before PCI and PCI without antibiotic prophylaxis. Significant differences were found by the Log-Rank Test over all groups (p < 0.001, df = 2) and in paired comparison PCI only versus coamoxiclav and PCI versus coamoxiclav + G-CSF (p < 0.001), coamoxiclav versus coamoxiclav plus G-CSF (p < 0.05) in the intent to treat analysis. B) Rats with ceftriaxone/metronidazole (Cef/met) prophylaxis (5/2 mg/kg), Cef/met plus G-CSF prophylaxis before PCI and PCI without antibiotic prophylaxis.Back to article page