Skip to main content

Table 6 Adverse events noted in patients treated with suppositories and parenteral treatment, by treatment group.

From: Rectal artemisinins for malaria: a review of efficacy and safety from individual patient data in clinical studies

 

Rectal artemisinin

Non-rectal artemisinin comparator

Non-artemisinin comparator (quinine)

TOTAL

Total no. patients included in analysis

786

253

123

1162

Total no. (%) of patients in whom one or more adverse event reported

140 (18)

24 (9)

30 (24)

194

Total no. of adverse events:

196

43

67

306

Classification (aetiology):

    

Possibly drug-related

37

14

27

78

Not likely to be drug related

105

28

40

173

Unable to be classified

54

1

0

55

Classification of possibly drug-related events according to body system:

    

   Generalised

11

1

0

12

   Neurological

1

1

7

9

   Digestive

18

10

8

36

   Urogenital

1

1

0

2

   Haemopoetic

3

1

4

8

   Special senses (hearing)

3

0

5

8

   Other

0

0

3

3