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Table 3 Agreement (κ coefficient) using CD4 count obtained by flow cytometry, CD4 percent by computational estimate, and total lymphocyte count (TLC) compared to CD4 percent obtained by flow cytometry for children not eligible for ART on clinical grounds, i.e. WHO stage I or II

From: Computed CD4 percentage as a low-cost method for determining pediatric antiretroviral treatment eligibility

Age group n CD4 count CD4 percent computational estimate TLC
Overall 170/125* 77.6% (0.39) 87.6% (0.71) 64.8% (0.04)*
≤ 11 months 41 78.0% (0.19) 87.8% (0.63) 80.5% (0.32)
12 to 35 months 22 68.2% (0.32) 95.4% (0.91) 54.5% (0.02)
36 to 59 months 21 71.4% (0.25) 71.4% (0.35) 47.6% (-0.32)
60 months to 96 months 41 85.4% (0.58) 92.7% (0.82) 63.4% (0.04)
≥ 96 months 45 77.8% (0.45) 86.7% (0.71) N/A†
  1. * 125 children aged between 0 and 8 years; † Total lymphocyte count (TLC) is not valid in children older than 8 years (n = 45)
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