Severe anaemia is not associated with HIV-1 env gene characteristics in Malawian children

BMC Infectious Diseases

Table 2 Markers of disease progression and outcome study group.

	Cases	Controls	p
Wasting (Z-score weight for height <-2)	7/36 (19%)	5/38 (13%)	0.46
Previous hospital admission	25/44 (57%)	16/41 (39%)	0.10
Mortality (18 months)	27/45 (60%)	6/41 (15%)	<0.001
During admission	7/45 (16%)	0/41 (0%)	0.01
After discharge	20/38 (53%)	6/41 (15%)	<0.001
Plasma viral load (mean ± SD in Log10/mL)	6.02 ± 1.08 n = 13	5.43 ± 0.85 n = 12	0.15
Severe immunodeficient (based on CD4%*)	9/16 (56%)	5/12 (42%)	0.45

Markers of disease progression in children with severe anaemia (cases Hb<5.0 g/dL) as compared to those without severe anaemia (controls). SD: Standard deviation; Viral loads were performed using a in-house methods as described in the method section. *According to the revised WHO guidelines CD4 <25% (6–12. months); <20% (12–35 months); <25% (36–59 months) [40].

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