Endothelin-1 precursor peptides correlate with severity of disease and outcome in patients with community acquired pneumonia

Table 2 Results of the receiver operating curve (ROC) characteristic plot analysis

Prediction of death (n = 35) in patients with CAP (n = 281)
Parameter	AUC	95% CI	P
ProET-1	0.64	0.53–0.74
PSI score	0.69	0.61–0.76	0.32
PSI/proET-1 combined	0.71	0.62–0.76	0.04
CURB65 score	0.67	0.57–0.77	0.51
CURB65/proET-1 combined	0.69	0.59–0.79	0.16
Prediction of adverse outcome (n = 61) in patients with CAP (n = 281)
Parameter	AUC	95% CI	P
ProET-1	0.69	0.61–0.77
PSI classes	0.71	0.65–0.78	0.57
PSI/proET-1 combined	0.75	0.68–0.81	0.06
CURB65 score	0.66	0.58–0.73	0.45
CURB65/proET-1 combined	0.69	0.62–0.77	0.75

CAP Community-acquired Pneumonia, AUC, Area Under the Curve; CI, Confidence Interval, PSI Pneumonia Severity Index, CURB65 Confusion – Urea – Respiration rate – Blood pressure – Age 65

ISSN: 1471-2334