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Table 3 Effect of ARV therapy on CD4 counts after 12 months.

From: Transmitted drug resistance, selection of resistance mutations and moderate antiretroviral efficacy in HIV-2: Analysis of the HIV-2 Belgium and Luxembourg database

  BASELINE CD4 (cells/mm3) DELTA CD4 after 12 months  
  Mean Median Interval   Mean Median Interval   
Non-treated (N = 10) 402 427 193 660 -16 -21 -112 64  
ARV therapies (n = 22) 263 226 10 737 64 50 -62 323  
- with PIs (n = 15) 230 237 10 527 106 89 -31 323 p = 0,0003
- without PIs (n = 7) 333 195 150 737 -25 -53 -62 57  
- undetectable VL (n = 8) 248 195 40 630 137 141 12 323 p < 0,0001
- detectable VL (n = 14) 272 226 10 737 23 16 -62 180  
  1. Interval columns give minimum and maximum CD4 cells/mm3. N is the number of patients for the untreated group, and n is the number of therapies in the treated group. p values were obtained by the analysis of variances using a Tukey test (see Methods section). PI = protease inhibitor, VL = plasma viral load.