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Table 3 Effect of ARV therapy on CD4 counts after 12 months.

From: Transmitted drug resistance, selection of resistance mutations and moderate antiretroviral efficacy in HIV-2: Analysis of the HIV-2 Belgium and Luxembourg database

 

BASELINE CD4 (cells/mm3)

DELTA CD4 after 12 months

 
 

Mean

Median

Interval

 

Mean

Median

Interval

  

Non-treated (N = 10)

402

427

193

660

-16

-21

-112

64

 

ARV therapies (n = 22)

263

226

10

737

64

50

-62

323

 

- with PIs (n = 15)

230

237

10

527

106

89

-31

323

p = 0,0003

- without PIs (n = 7)

333

195

150

737

-25

-53

-62

57

 

- undetectable VL (n = 8)

248

195

40

630

137

141

12

323

p < 0,0001

- detectable VL (n = 14)

272

226

10

737

23

16

-62

180

 
  1. Interval columns give minimum and maximum CD4 cells/mm3. N is the number of patients for the untreated group, and n is the number of therapies in the treated group. p values were obtained by the analysis of variances using a Tukey test (see Methods section). PI = protease inhibitor, VL = plasma viral load.