Table 1 Potential sepsis related markers (modified from reference 18)
From: Toward an operative diagnosis in sepsis: a latent class approach
General Variables |
|---|
Temperature > 38.3°C or < 36°C |
Heart rate > 90 beats min-1 |
Tachypnea (respiratory rate > 20 breaths min-1 in adults) |
Altered mental status |
Inflammatory variables |
WBC > 12,000 μL-1, < 4,000 μL-1 or with > 10% immature forms |
Plasma C-reactive protein > 2 SD above the normal value |
Plasma procalcitonin > 2 SD above the normal value |
Hemodynamic variables |
Systolic blood pressure < 90 mm Hg or mean arterial blood pressure < 70 mm Hg |
Mixed venous oxygen saturation > 70% |
Cardiac index > 3.5 L*min-1*M-23 |
Organ dysfunction variables |
PaO2/FIO2 < 300 |
Urine output < 0.5 mL*kg-1*hr-1 or creatinine increase > 0.5 mg/dL |
International normalized ratio (INR) > 1.5 or aPTT > 60 secs |
Platelet count < 100,000 μL-1 |
Plasma total bilirrubin > 4 mg/Dl |
Tissue perfusion variables |
Hyperlactatemia > 1 mmol/L |
Decreased capillary refill or mottling |