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Table 2 Description of the blood stream infection episodes at the time of the first positive blood culture drawing according to the sepsis type (i.e. primary or secondary sepsis).

From: Impact of previous sepsis on the accuracy of procalcitonin for the early diagnosis of blood stream infection in critically ill patients

Mean (SD) or number (%) Primary sepsis n = 117 Secondary sepsis n = 62 p
Time elapsed from ICU admission (N. of days) 2.0 (2.4) 15.6 (16.9) < 0.0001
SOFA score 6.9 (4.1) 7.2 (3.9) 0.706
Platelet count (cell/mm3) 185,459 (118,375) 235,935 (183,485) 0.028
Creatininemia (μmol/L) 198.7 (168.5) 163.2 (129.2) 0.149
Prothrombin time (%) 58.8 (21.9) 62.8 (19.9) 0.248
Septic shock 60 (51.7) 31 (50.0) 0.302
Nosocomial sepsis ICU acquired sepsis 34 (35.8) 31 (26.5) 62 (100) 52 (83.9) < 0.0001 < 0.0001
Infection source    0.002
Lung 30 (25.6) 12 (19.3) 0.447
Abdominal 23 (19.7) 18 (29.0) 0.217
Soft tissues 13 (11.1) 4 (6.4) 0.456
Urinary tract 24 (20.5) 2 (3.2) 0.004
Miscellaneous 9 (7.7) 5 (8.1) 0.480
Unknown 18 (15.4) 21 (33.9) 0.008
Involved pathogen bacteria 113 (95.6) 41 (64.4) < 0.0001
Gram positive 51 (43.6) 20 (32.2)  
Gram negative 62 (53.0) 21 (33.9)  
fungi    
Candida spp 4 (3.4) 21 (33.9)  
Previous exposure to antibiotic therapy with in vitro activity against the involved pathogen 16 (13.7) 21 (33.9) 0.003
Previous exposure to steroids 9 (7.7) 23 (37.1) < 0.0001
Time elapsed between bacteremia onset and PCT sampling (N. of minutes)    
Mean (SD) -169.7 (382.6) 6.3 (455.4) 0.011
Median [range] -13.0 [-1072–720] 0.0 [-720–720]  
  1. ICU: Intensive Care Unit; SOFA: Sepsis-related Organ Failure Assessment.