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Table 3 Results of the statistical tests determining if there was a significant change in antibody level between the two time points (pre and post-treatment) and subsequently if any significant changes were related to praziquantel treatment

From: Effect of treating Schistosoma haematobium infection on Plasmodium falciparum-specific antibody responses

 

T-test

Multi-variate analysis

Response

Z-value

P-value (2 tailed)

F-value

P-value

WWH-IgG1

-3.424

0.001

4.083

0.046

WWH-IgG3

-1.206

0.228

0.054

0.816

MSP2 (CH150)-IgG1

-0.927

0.354

0.012

0.914

MSP2 (CH150)-IgG3

-1.658

0.098

0.068

0.974

MSP2 (Dd2)-IgG1

-3.386

0.001

0.135

0.714

MSP2 (Dd2)-IgG3

-0.895

0.371

0.849

0.359

MSP1 (DPK)-IgG1

-0.738

0.460

0.094

0.760

MSP1 (DPK)-IgG3

-1.885

0.059

0.676

0.413

MSP1 (MSP119)-IgG1

-3.292

0.001

0.524

0.471

MSP1 (MSP119)-IgG3

-3.927

0.000

0.069

0.793

Schizont-IgG1

-2.342

0.019

0.018

0.894

Schizont-IgG3

-0.970

0.332

0.227

0.635

  1. A 2-tailed Wilcoxon nonparametric test for related samples was used to determining if there was a difference between the two time points (antibody data were not normally distributed even after transformations). A multi-variate analysis of variance was used to determined if any significant differences between the two time points were related to treatment. Residuals from this parametric test were normally distributed. The degrees of freedom for this were 1 and 117. For both tests P-values < 0.05 are highlighted in bold.