Table 1 Baseline characteristics of all patients and according to the maximum procalcitonin levels measured (PCTmax)
From: Procalcitonin levels in acute exacerbation of COPD admitted in ICU: a prospective cohort study
Characteristics | AECOPD n = 39* | PCTmax<0.1 n = 14 | 0.1<PCTmax<0.25 n = 11 | PCTmax>0.25 n = 10 |
|---|---|---|---|---|
Age, yr | 62 ± 15 | 54 ± 16 | 71 ± 10 | 66 ± 7 |
Male sex, no.(%) | 26(67) | 7(50) | 8(73) | 9(90) |
SAPS II score¶ | 30 [23–35] | 25 [18–30] | 31 [26–33] | 39 [28–40] |
APACHE II score¶¶ | 18 [12–23] | 13 [9–23] | 18 [16–22] | 19 [18–26] |
LOD score¶¶¶ | 4 [2–5] | 3 [2–4] | 4 [2–4] | 5 [3–8] |
Comorbidities, no. (%) | ||||
Current smokers, | 11(28) | 4(29) | 4(36) | 3(30) |
Chronic alcohol abuse | 8(20) | 3(21) | 2(18) | 2(20) |
Obesity | 8(20) | 2(14) | 4(36) | 2(20) |
Coronary artery disease | 4(10) | 1(7) | 0 | 3(30) |
Hypertensive heart disease | 15(38) | 4(29) | 4(36) | 5(50) |
Congestive heart disease | 2(5) | 0 | 1(9) | 0 |
Diabetes mellitus | 13(33) | 6(42) | 4(36) | 3(30) |
Chronic Pseudomonas colonization, no. (%) | 5(13) | 3(21) | 0 | 2(20) |
Severity of COPD¶¶¶¶, no. (%) | ||||
GOLD stage I (mild) | 7(18) | 4(29) | 1(9) | 0 |
GOLD stage II (moderate) | 3(8) | 1(7) | 2(18) | 0 |
GOLD stage III (sever) | 3(8) | 0 | 2(18) | 1(10) |
GOLD stage IV (very sever) | 26(67) | 9(64) | 6(54) | 9(90) |
Home oxygen, no. (%) | 22(56) | 8(57) | 5(45) | 8(80) |
Home non-invasive ventilation, no. (%) | 5(13) | 2(14) | 0 | 2(20) |
Oral or inhaled steroid, no. (%) | 23(59) | 8(57) | 7(64) | 8(80) |
Examination at ICU admission, no. (%) | ||||
Dyspnea | 39(100) | 14(100) | 11(100) | 10 |
Cough | 17(44) | 5(35) | 8(73) | 4(40) |
Sputum | 15(33) | 5(36) | 5(45) | 5(50) |
Rales | 4(10) | 1(7) | 1(9) | 2(20) |
Wheezing | 30(77) | 11(100) | 10(90) | 7(70) |
Body temperature,°C | 37.0 ± 0.8 | 36.7 ± 0.9 | 37.2 ± 0.5 | 37.2 ± 0.8 |
Leucocytes count ((×109/L) | 11.5 ± 4.3 | 9.3 ± 4.1 | 11.2 ± 4.6 | 14.2 ± 2.9 |
CRP-H0 | 19 [9–60] | 13 [8–22] | 15 [5–66] | 43 [11–156] |
CRP-H24 | 21 [11–34] | 21 [11–24] | 17 [9–32] | 78 [11–106] |