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Table 3 Impact of patient characteristics on outcomes measured

From: Epidemiology and outcomes of community-onset methicillin-susceptible Staphylococcus aureusbacteraemia in a university hospital in Singapore

Characteristic

Complicated bacteraemia

Attributable mortality

Complicated and/or recurrent infection

 

Odds ratio [CI]

p-value

Odds ratio [CI]

p-value

Odds ratio [CI]

p-value

Demographics:

      

Age > 65 years

1.39 [0.59–3.24]

0.45

13.70 [2.75–68.29]

< 0.01

0.48 [0.19–1.22]

0.12

Male gender

0.82 [0.36–1.88]

0.64

1.07 [0.29–3.94]

0.92

1.01 [0.43–2.36]

0.98

Ethnicity

1.59 [0.95–2.64]

0.08

1.10 [0.52–2.36]

0.80

1.73 [1.03–2.90]

0.04

Healthcare-associated infection

0.51 [0.23–1.14]

0.10

1.34 [0.38–4.72]

0.65

0.43 [0.19–1.00]

0.05

Co-morbidities:

      

Diabetes mellitus

0.55 [0.24–1.25]

0.15

0.58 [0.14–2.33]

0.44

0.68 [0.29–1.60]

0.38

Dialysis-dependent renal failure

0.71 [0.32–1.57]

0.40

3.27 [0.81–13.13]

0.10

0.36 [0.15–0.84]

0.02

Malignancy

0.42 [0.12–1.44]

0.17

2.66 [0.61–11.56]

0.19

0.24 [0.05–1.15]

0.08

Chronic pulmonary disease

1.88 [0.50–7.10]

0.36

14.00 [3.15–62.17]

< 0.01

0.17 [0.02–1.37]

0.10

Valvular heart disease

5.47 [1.10–27.25]

0.04

2.25 [0.41–12.26]

0.35

2.85 [0.75–10.88]

0.12

Other risk factors:

      

Intravenous drug abuse

4.92 [1.48–16.41]

< 0.01

-*

-*

7.99 [2.37–26.98]

< 0.01

Presence of intravenous catheter

0.53 [0.21–1.34]

0.18

2.70 [0.75–9.74]

0.14

0.31 [0.11–0.92]

0.03

Previous hospitalization

0.68 [0.31–1.50]

0.34

2.61 [0.65–10.47]

0.18

0.54 [0.24–1.22]

0.14

Inappropriate empiric therapy

0.57 [0.10–3.25]

0.55

4.72 [0.75–29.5]

0.10

-*

-*

Suboptimal therapy

Not applicable

-

2.91 [0.82–10.37]

0.10

Not applicable

-

  1. * This calculation predicted failure in a significant way. No intravenous drug abuser died from S. aureus bacteremia, and none of the patients with complicated and/or recurrent infections received inappropriate empiric therapy.