Skip to main content

Table 3 Mean percentages of naïve and memory T cells in 12–15 year old CMV seronegative and seropositive UK adolescents.

From: Differences between naive and memory T cell phenotype in Malawian and UK adolescents: a role for Cytomegalovirus?

   CD4+ CD8+ p value
   CMV
seronegative
CMV
seropositive
CMV
seronegative
CMV
seropositive
CD4+ CD8+
   n = 19 n = 10 n = 19 n = 10   
%CCR7 na&#239ve
(i.e. CD45RA+CCR7+)a
(range) 46 (2–79) 34 (1–57) 60 (43–87) 40 (15–58) 0.14 <0.001
%CCR7 memory that are central memory
(i.e. CD45RA-CCR7+)b
(range) 54 (2–90) 41 (19–74) 32 (0–73) 14 (1–36) 0.16 0.021
%CCR7 memory that are effector memory
(i.e. CD45RA-CCR7-)c
(range) 26 (4–45) 35 (20–50) 27 (0–48) 33 (10–56) 0.06 0.27
%CCR7 memory that are stable memory
(i.e. CD45RA+CCR7-)d
(range) 21 (0–95) 24 (0–56) 41 (15–100) 52 (9–83) 0.72 0.21
   n = 18 n = 9 n = 15 n = 11   
% "truly naïve" (range) 75 (55–87) 69 (57–77) 63 (28–80) 51 (39–66) 0.06 0.02
   n = 18 n = 11 n = 18 n = 11   
% CD28-memory
(CD28-CD45RO+) T cells
(range) 0.2 (0–0.9) 0.7 (0–2.6) 2.5 (0.4–8.1) 4.4 (0–12.4) 0.03 0.19
  1. Ranges are minimum and maximum values.
  2. a Proportion of all CCR7 cells that are naïve. b, c, d Of the CCR7 cells that are memory, proportion that are either central memory (b), effector memory (c) or stable memory (d) (percentages in b, c and d sum to 100).