Skip to main content

Advertisement

Table 1 Total number of blood cultures taken and analysed over the four years 2003–2006 inclusive and the proportion of cultures growing a contaminant or significant isolate

From: Blood culture collection technique and pneumococcal surveillance in Malawi during the four year period 2003–2006: an observational study

Year 2003 2004 2005 2006 P1 OR2
Total blood cultures 7141 5709 6129 5650   
Contaminants n(%) 1402(19.6) 1071(18.8) 442(7.2) 280(5.0) < 0.01 0.27
All significant isolates 1267(17.7) 931(16.3) 1203(19.6) 1020(18.1) < 0.01 1.13
S. pneumoniae 207(2.9) 152(2.7) 410(6.7) 310(5.5) < 0.01 2.26
non-typhoidal Salmonella 758(10.6) 483(8.5) 480(7.8) 374(6.6) < 0.01 0.73
C. neoformans 64(0.9) 53(0.9) 73(1.2) 118(2.1) < 0.01 1.79
E. coli 93(1.3) 76(1.3) 114(1.9) 115(2.0) < 0.01 1.48
Klebsiella spp 25(0.4) 24(0.4) 13(0.2) 12(0.2) 0.02 0.55
S. aureus 38(0.5) 43(0.8) 26(0.4) 16(0.3) < 0.01 0.56
Group A streptococcus 10(0.1) 12(0.2) 15(0.2) 15(0.3) 0.15  
S. typhi 3(0.0) 3(0.1) 8(0.1) 11(0.2) < 0.01 3.46
Other Gram positive 3 19(0.3) 34(0.6) 27(0.4) 16(0.3) 0.55  
Other Gram negative 4 50(0.7) 51(0.9) 37(0.6) 33(0.6) 0.07  
Median volume ml (IQR) 4.6(0.3–10.1)   9.7(1.9–13.3)2   < 0.001  
  1. 1 The p value has been derived by a two-way comparison comparing 2003/4 (pre-dedicated culture service) vs 2005/6 (post dedicated service) using a chi2 test. 2 The odds ratio of recovery during the 2005/6 blood culture intervention year compared to the pre-blood culture service period. 3 Other Gram positive isolates were primarily non-pneumococcal alpha haemolytic Streptococci (72 of 96, 75%) 4 Other Gram negative isolates included Haemophilus spp. (16 of 171, 9.4%), Pseudomonas spp. (18, 10.5%), Neisseria meningitidis (14, 8.2%), Acinetobacter spp. (32, 18.7%), Enterobacter spp. (38, 22.4%) and other coliforms (53, 31.0%).