From: Outcome of HIV-associated Pneumocystis pneumonia in hospitalized patients from 2000 through 2003
Univariate predictors | All subjects (n = 292) OR (95% CI), p-value | Empiric (n = 127) OR (95% CI), p-value | Definitive (n = 165) OR (95% CI), p-value |
---|---|---|---|
Mechanical ventilation | 18.0 (7.9–41.1), < 0.001 | 86.3 (13.1–568.3), <0.001 | 9.6 (3.8–24.7), < 0.001 |
Pneumothorax | 10.3 (3.9–27.3), < 0.001 | _* | 10.2 (3.5–29.7), < 0.001 |
Serum LDH (per 100 U/l increase) | 1.3 (1.09–1.65), 0.005 | 1.3 (0.79–2.02), 0.33 | 1.3 (1.02–1.63), 0.03 |
Serum albumin (per 0.1 g/dl increase) | 0.32 (0.17–0.60), < 0.001 | 0.27 (0.09–0.88), 0.02 | 0.36 (0.17–0.77), 0.008 |
Empiric diagnosis | 0.36 (0.16–0.82), 0.02 | _ | _ |
Alveolar-arterial oxygen gradient (per 1 mm Hg increase)(n = 129) | 1.08 (1.03–1.12), 0.001 | 1.05 (0.98–1.12), p = 0.16 | 1.10 (1.03–1.17), p = 0.003 |
Multivariate predictors (n = 278) | Â | Â | Â |
Pneumothorax | 15.7 (4.4–56.4), < 0.001 |  |  |
Mechanical ventilation | 14.8 (5.7–38.9), < 0.001 |  |  |
Serum albumin (per 0.1 g/dl increase) | 0.27 (0.12–0.61), 0.002 |  |  |