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Figure 1 | BMC Infectious Diseases

Figure 1

From: Utility of interferon-γ ELISPOT assay responses in highly tuberculosis-exposed patients with advanced HIV infection in South Africa

Figure 1

Proportion of positive IFN-γ ELISPOT responses and 7-day IFN-γ whole blood assay (WBA) responses to ESAT-6 and/or CFP-10 (RD1) and purified protein derivative (PPD) among HIV- controls (n = 30) and HIV+ patients (n = 40) subdivided into those with (n = 19) or without (n = 21) a history of previous tuberculosis treatment (TB Rx). ELISPOT assay responses in HIV+ patients were strongly associated with history of TB treatment. *In HIV+ patients who had previously received TB treatment, the proportions of positive responses to RD1 and PPD antigens were significantly lower using the ELISPOT assay than the WBA (P < 0.05 for each comparison). ns = not significant.

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