Figure 3
From: The pathogen recognition sensor, NOD2, is variably expressed in patients with pulmonary tuberculosis
NOD2 mRNA expression correlates with TLR2 and TLR4 mRNA expression in pulmonary leucocytes harvested from patients with tuberculosis. A significant correlation was observed between mRNA molecules encoding NOD2 and toll-like receptor (TLR) 2 (p = 0.02) [A] and TLR4 (p = 0.01) [B] in pulmonary leucocytes harvested from patients with tuberculosis. To permit correlations, absolute copy numbers of NOD2 and TLR2, TLR4 and TLR6 mRNA were measured during RT-PCR, using cDNA standards, and expressed relative to 106 mRNA copies of a validated housekeeping gene HuPO.