Figure 1From: Analysis of multiple single nucleotide polymorphisms closely positioned in the ovine PRNPgene using linear fluorescent probes and melting curve analysis Detection of additional polymorphisms with the 136 HyBeacon. (A) The T137 polymorphism is detected as a melting peak at approximately 59.5°C and is clearly distinct from the A136 and V136 peaks at 62.0°C and 53.2°C respectively. (B) T136 is detected as a melting peak at approximately 56.9°C, enabling clear differentiation of genotypes such as ARR/VRQ and ARR/TRQ.Back to article page