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Table 1 Association between cumulative mortality within 1 year and patient characteristics in 326 episodes of infective endocarditis

From: Short-term and one-year outcome of infective endocarditis in adult patients treated in a Finnish teaching hospital during 1980–2004

  Mortality during n (%)
  N In-hospitala p value 3 months p value 6 months p value 1 year p value
Sex    0.423   0.261   0.328   0.707
   Male 234 35 (15.0)   34 (14.7)   38 (16.5)   39 (17.0)  
   Female 92 11 (12.0)   9 (9.9)   11 (12.1)   14 (15.7)  
Age    0.065   0.022   0.013   0.004
   18–64 years 209 23 (11.0)   21 (10.2)   24 (11.6)   25 (12.1)  
   ≥65 years 117 23 (19.7)   22 (19.0)   25 (21.8)   28 (24.9)  
Etiology    0.031b   0.004b   0.012b   0.036b
   Staphylococcus aureus 75 14 (18.7)   14 (18.9)   15 (20.3)   15 (20.3)  
   CoNSc 31 6 (19.4)   6 (19.4)   6 (19.4)   6 (19.4)  
   Viridans streptococci 67 10 (14.9)   8 (12.0)   11 (16.8)   12 (18.4)  
   Enterococcus faecalis 25 2 (8.0)   2 (8.0)   2 (8.0)   3 (12.8)  
   Streptococcus pneumoniae 11 5 (45.5)   5 (45.5)   5 (45.5)   5 (45.5)  
   Other 28 2 (7.1)   1 (3.6)   2 (7.3)   2 (7.3)  
   Negative 89 7 (7.9)   7 (8.1)   8 (9.2)   10.(11.6)  
Affected valves    <0.001b   <0.001b   <0.001b   <0.001b
   Aortic 113 16 (14.2)   15 (13.4)   16 (14.4)   17 (15.4)  
   Mitral 96 6 (6.3)   7 (7.3)   8 (8.4)   9 (9.5)  
   Tricuspid 18 2 (11.1)   1 (5.9)   2 (11.8)   2 (11.8)  
   Two native valves 32 14 (43.8)   13 (40.6)   14 (43.8)   15 (46.9)  
   Prosthetic valve(s) 67 8 (11.9)   7 (10.6)   9 (13.7)   10 (15.3)  
Echocardiography          
   Major criterion    0.343   0.090   0.028   0.012
Yes 221 37 (16.7)   34 (15.6)   40 (18.4)   44 (20.4)  
No 105 9 (8.6)   9 (8.7)   9 (8.7)   9 (8.7)  
   Vegetation    0.097   0.047   0.010   0.003
Yes 198 36 (18.2)   32 (16.3)   38 (19.5)   42 (21.7)  
No 128 10 (7.8)   11 (8.7)   11 (8.7)   11 (8.7)  
Neurological events d    0.009   0.003   0.003   0.005
Yes 86 21 (24.4)   19 (22.5)   21 (24.9)   22 (26.1)  
No 240 25 (10.4)   24 (10.1)   28 (11.8)   31 (13.2)  
Peripheral emboli d    0.032   0.073   0.016   0.022
Yes 102 22 (22.0)   18 (18.3)   22 (22.6)   23 (23.7)  
No 224 24 (10.6)   25 (11.1)   27 (12.1)   30 (13.5)  
Heart failure d    <0.001   <0.001   <0.001   <0.001
Yes 178 41 (23.0)   38 (21.8)   44 (25.5)   47 (27.5)  
No 148 5 (3.4)   5 (3.4)   5 (3.4)   6 (4.1)  
In-hospital surgery    0.751   0.614   0.551   0.552
Yes 89 15 (16.9)   13 (14.7)   15 (17.0)   16 (18.2)  
No 237 31 (13.1)   30 (12.8)   34 (14.6)   37 (16.0)  
CRP on admission e    0.005   <0.001   <0.001   <0.001
   ≥100 mg/l 148 28 (18.9)   29 (19.7)   31 (21.1)   34 (23.3)  
   < 100 mg/l 124 8 (6.5)   5 (4.1)   8 (6.6)   8 (6.6)  
Creatinine on admission f    0.075   0.017   0.052   0.160
   ≥100 μmol/l 108 28 (18.9)   19 (17.7)   19 (17.7)   19 (17.7)  
   < 100 μmol/l 174 17 (9.8)   15 (8.7)   18 (10.4)   22 (12.8)  
  1. aMean (SD) duration of in-hospital treatment was 55 (33), range 4 to 272 days; bp values for overall group differences; ccoagulase-negative staphylococci; dwithin 3 months from admission; edata available for 272 episodes; fdata available for 282 episodes