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Table 1 Antiviral treatment schedule and effects

From: Influenza pandemic intervention planning using InfluSim: pharmaceutical and non- pharmaceutical interventions

Parameter Value Source
Average time for seeking medical help after symptom onset D D = 24 h assumed
therapeutic window (after onset of symptoms) D T = 48 h Fachinformation Roche
fraction eligible to receive treatment   assumed
   • severe cases who can stay at home f V = 100%  
   • extremely severe cases who need hospitalization f X = 100%  
treatment reduces the duration of the infectious period f D = 25% Fachinformation Roche
treatment reduces infectiousness by f I = 80% Longini (2004)
treatment reduces hospitalizations by f H = 50% Kaiser (2003)