Table 1 Antiviral treatment schedule and effects
Parameter | Value | Source |
|---|---|---|
Average time for seeking medical help after symptom onset | D D = 24 h | assumed |
therapeutic window (after onset of symptoms) | D T = 48 h | Fachinformation Roche |
fraction eligible to receive treatment | assumed | |
• severe cases who can stay at home | f V = 100% | |
• extremely severe cases who need hospitalization | f X = 100% | |
treatment reduces the duration of the infectious period | f D = 25% | Fachinformation Roche |
treatment reduces infectiousness by | f I = 80% | Longini (2004) |
treatment reduces hospitalizations by | f H = 50% | Kaiser (2003) |