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Table 1 Characteristics of HIV-infected pregnant women in PACTG 316, USA versus Europe

From: Characteristics and management of HIV-1-infected pregnant women enrolled in a randomised trial: differences between Europe and the USA

Characteristics

USA

Europe

Total

p-value*

Total mothers delivered

978

372

1350

 

Median age: entry (IQR)

27.2 (22.9–31.8)

30 (26.9–34)

28.1 (23.9–32.4)

<0.0001

Ethnicity

   

<0.0001

White

119 (12%)

190 (51%)

309 (23%)

 

Black

621 (64%)

172 (46%)

793 (59%)

 

Hispanic

223 (23%)

8 (2%)

231 (17%)

 

Other

15 (1.5%)

2 (0.5%)

17 (1%)

 

Parity

   

0.0001

0–1

161 (17%)

80 (22%)

241 (18%)

 

2–3

399 (41%)

168 (45%)

567 (42%)

 

4–5

267 (27%)

97 (26%)

364 (27%)

 

≥6

151 (15%)

27 (7%)

178 (13%)

 

Previous miscarriages

   

<0.0001

0

707 (72%)

325 (87%)

1032 (76%)

 

1–2

247 (25%)

44 (12%)

291 (22%)

 

3–6

24 (2.5%)

3 (1%)

27 (2%)

 

Previous terminations

   

<0.0001

0

710 (73%)

192 (52%)

902 (67%)

 

1–2

220 (22%)

149 (40%)

369 (27%)

 

3–4

41 (4%)

28 (7%)

69 (5%)

 

5–12

7 (1%)

3 (1%)

10 (1%)

 

Timing of HIV diagnosis

   

<0.0001

Pre-pregnancy

539 (55%)

259 (70%)

798 (59%)

 

Antenatal

439 (45%)

112 (30%)

551 (41%)

 

Mode of acquisition #

    

Sexual with HIV at risk

336 (34%)

44 (12%)

380 (28%)

<0.0001

Sexual with HIV positive

214 (22%)

105 (28%)

319 (24%)

0.0623

Sexual with HIV unknown

716 (73%)

162 (44%)

878 (65%)

<0.0001

Current IDU

12 (1%)

11 (3%)

23 (2%)

0.0331

Previous IDU

68 (7%)

35 (9%)

103 (8%)

0.1340

Blood transfusion

20 (2%)

7 (2%)

27 (2%)

0.9999

Occupational risk

22 (2%)

3 (1%)

25 (2%)

0.1108

Other risk factor

44 (4%)

8 (2%)

52 (4%)

<0.0001

Unknown risk factor

47 (5%)

46 (12%)

93 (7%)

0.0401

STD history

   

<0.0001

Yes

280 (29%)

19 (5%)

299 (22%)

 

No

450 (46%)

353 (95%)

803 (60%)

 

Unknown

248 (25%)

0 (0)

248 (18%)

 
  1. # Some women reported multiple risk factors
  2. * for the difference USA versus Europe