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Table 1 Characteristics of HIV-infected pregnant women in PACTG 316, USA versus Europe

From: Characteristics and management of HIV-1-infected pregnant women enrolled in a randomised trial: differences between Europe and the USA

Characteristics USA Europe Total p-value*
Total mothers delivered 978 372 1350  
Median age: entry (IQR) 27.2 (22.9–31.8) 30 (26.9–34) 28.1 (23.9–32.4) <0.0001
Ethnicity     <0.0001
White 119 (12%) 190 (51%) 309 (23%)  
Black 621 (64%) 172 (46%) 793 (59%)  
Hispanic 223 (23%) 8 (2%) 231 (17%)  
Other 15 (1.5%) 2 (0.5%) 17 (1%)  
Parity     0.0001
0–1 161 (17%) 80 (22%) 241 (18%)  
2–3 399 (41%) 168 (45%) 567 (42%)  
4–5 267 (27%) 97 (26%) 364 (27%)  
≥6 151 (15%) 27 (7%) 178 (13%)  
Previous miscarriages     <0.0001
0 707 (72%) 325 (87%) 1032 (76%)  
1–2 247 (25%) 44 (12%) 291 (22%)  
3–6 24 (2.5%) 3 (1%) 27 (2%)  
Previous terminations     <0.0001
0 710 (73%) 192 (52%) 902 (67%)  
1–2 220 (22%) 149 (40%) 369 (27%)  
3–4 41 (4%) 28 (7%) 69 (5%)  
5–12 7 (1%) 3 (1%) 10 (1%)  
Timing of HIV diagnosis     <0.0001
Pre-pregnancy 539 (55%) 259 (70%) 798 (59%)  
Antenatal 439 (45%) 112 (30%) 551 (41%)  
Mode of acquisition #     
Sexual with HIV at risk 336 (34%) 44 (12%) 380 (28%) <0.0001
Sexual with HIV positive 214 (22%) 105 (28%) 319 (24%) 0.0623
Sexual with HIV unknown 716 (73%) 162 (44%) 878 (65%) <0.0001
Current IDU 12 (1%) 11 (3%) 23 (2%) 0.0331
Previous IDU 68 (7%) 35 (9%) 103 (8%) 0.1340
Blood transfusion 20 (2%) 7 (2%) 27 (2%) 0.9999
Occupational risk 22 (2%) 3 (1%) 25 (2%) 0.1108
Other risk factor 44 (4%) 8 (2%) 52 (4%) <0.0001
Unknown risk factor 47 (5%) 46 (12%) 93 (7%) 0.0401
STD history     <0.0001
Yes 280 (29%) 19 (5%) 299 (22%)  
No 450 (46%) 353 (95%) 803 (60%)  
Unknown 248 (25%) 0 (0) 248 (18%)  
  1. # Some women reported multiple risk factors
  2. * for the difference USA versus Europe