Table 2 Factors associated with virological response (univariate and multivariate analyses).
Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
OR (95% CI) | p | OR (95% CI) | ||
Rescue with PI/rit | 3.93 (0.88 to 17.56) | 0.07 | 7.57 (0.58 to 99.31) | 0.12 |
Previous length of ARV exposure | 0.99 (0.97 to 1.01) | 0.29 | - | - |
Previous length of PI exposure | 0.98 (0.94 to 1.01) | 0.19 | - | - |
No. previous PIs exposure | 0.61 (0.29 to 1.25) | 0.18 | 0.23 (0.06 to 0.89) | 0.03 |
No. susceptible drugs according to CCO1 | 2.16 (1.02 to 4.57) | 0.04 | 0.22 (0.03 to 1.57) | 0.13 |
No. susceptible drugs according to CCO2 | 4.99 (1.55 to 16.05) | 0.01 | 5.34 (1.23 to 23.11) | 0.02 |
No. active PIs in the salvage regimen according to virtual phenotype | 6.60 (1.40 to 31.05) | 0.02 | 0.64 (0.03 to 11.58) | 0.76 |
No. NAMs | 0.85 (0.54 to 1.32) | 0.46 | - | - |
No. protease resistance mutations | 0.81 (0.62 to 1.06) | 0.12 | 0.89 (0.56 to 1.46) | 0.65 |