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Table 1 Outcome of clinical and laboratory investigations in absolute numbers in the convent population (N = 99)

From: Sensitivity and specificity of single IgA and IgG antibody concentrations for early diagnosis of pertussis in adults: an evaluation for outbreak management in public health practice

Outcome of laboratory tests for pertussis infection Clinical Outcome Total
  Clinical pertussis coughing > 14 days Clinical pertussis coughing 7–13 days Pre-epidemic cough No cough  
  (n = 47)c (n = 3)c (n = 2) (n = 47)e (N = 99)
Laboratory confirmed pertussis infection: 45b 1b 0 12f 58
IgA or IgG 4-fold increase or decrease between week 9, 13 and 60 of the epidemic 41 1 0 9 51
IgG ≥ 100 U/ml at week 9 or 13 of the epidemic, no IgA or IgG 4-fold increase or decrease 4 0 0 3 7
Details of laboratory confirmed pertussis findings:      
- IgG ≥ 100 U/ml 41 0 0 6 47
- IgA 4-fold increase 8 1 0 2 11
- IgA 4-fold increase or decrease 22 1 0 5 28
- IgG 4-fold increase 6 1 0 2 9
- IgG 4-fold increase or decrease 39 1 0 9 49
- PCR or culture positive a 5 0 0 0 5
No laboratory confirmed pertussis infection 2 2 2 35d 41
  1. a All culture and PCR positive subjects had a significant increase of IgA or IgG as well
  2. b Pertussis cases for sensitivity calculation
  3. c Subjects for calculations of spectrum bias in sensitivity
  4. d Internal controls for specificity calculation
  5. e Subjects with no cough for calculations of spectrum bias in specificity
  6. f Subjects with asymptomatic pertussis infection