Table 1 Reduction of viral infectivity (log10 steps) obtained with three alcohol-based hand rubs (A: based on 45% isopropanol, 30% n-propanol and 0.2% mecetronium etilsulfate; B: based on 80% ethanol; C: based on 95% ethanol) against the six different enveloped viruses with different types of organic load.
Hand rub | Type of organic load* | BVDV | Vaccinia virus | HSV 1 | HSV 2 | Human influenza A virus | Avian influenza A virus | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
reduction of viral infectivity (log10-steps) within a defined contact time** | |||||||||||||||||||
15 s | 30 s | 60 s | 15 s | 30 s | 60 s | 15 s | 30 s | 60 s | 15 s | 30 s | 60 s | 15 s | 30 s | 60 s | 15 s | 30 s | 60 s | ||
A | None | ≥ 4.3 | ≥ 6.3 | ≥ 4.0 | ≥ 4.8 | ≥ 4.3 | ≥ 5.1 | ||||||||||||
10% FCS | ≥ 4.3 | ≥ 5.3 | ≥ 4.3 | ≥ 4.8 | ≥ 4.4 | ≥ 5.3 | |||||||||||||
0.2% BSA | ≥ 4.8 | ≥ 5.6 | ≥ 4.0 | ≥ 5.0 | ≥ 4.3 | ≥ 5.3 | |||||||||||||
"clean conditions" | ≥ 4.7 | ≥ 5.7 | ≥ 4.4 | ≥ 4.1 | ≥ 4.4 | ≥ 5.0 | |||||||||||||
"dirty conditions" | ≥ 4.5 | ≥ 6.4 | ≥ 4.4 | ≥ 4.1 | ≥ 4.0 | ≥ 5.4 | |||||||||||||
B | None | ≥ 4.3 | ≥ 5.0 | ≥ 4.4 | ≥ 4.4 | ≥ 4.3 | ≥ 5.1 | ||||||||||||
10% FCS | ≥ 4.0 | ≥ 5.3 | ≥ 4.4 | ≥ 4.4 | ≥ 4.4 | ≥ 5.3 | |||||||||||||
0.2% BSA | ≥ 4.0 | ≥ 5.3 | ≥ 4.4 | ≥ 4.4 | ≥ 4.3 | ≥ 5.3 | |||||||||||||
"clean conditions" | ≥ 4.0 | ≥ 5.0 | ≥ 4.6 | ≥ 4.5 | ≥ 4.4 | ≥ 5.0 | |||||||||||||
"dirty conditions" | ≥ 4.2 | ≥ 5.4 | ≥ 4.5 | ≥ 4.6 | ≥ 4.0 | ≥ 5.4 | |||||||||||||
C | None | ≥ 4.4 | ≥ 4.8 | ≥ 4.3 | ≥ 4.4 | ≥ 4.3 | ≥ 5.1 | ||||||||||||
10% FCS | ≥ 4.5 | ≥ 4.5 | ≥ 4.3 | ≥ 4.4 | ≥ 4.4 | ≥ 5.3 | |||||||||||||
0.2% BSA | ≥ 4.9 | ≥ 4.1 | ≥ 4.0 | ≥ 4.4 | ≥ 4.3 | ≥ 5.3 | |||||||||||||
"clean conditions" | ≥ 4.9 | ≥ 4.5 | ≥ 4.4 | ≥ 4.0 | ≥ 4.4 | ≥ 5.0 | |||||||||||||
"dirty conditions" | ≥ 4.7 | ≥ 5.5 | ≥ 4.0 | ≥ 4.4 | ≥ 4.0 | ≥ 5.4 | |||||||||||||