Table 5 Logistic regression analysis of risk factors for intra-hospital death from laboratory-confirmed bloodstream infection and clinically suspected systemic infection
Characteristic | Laboratory-confirmed bloodstream infection | Clinically suspected systemic infection | ||
|---|---|---|---|---|
HIV-status analyzed | No | Yes | No | Yes |
No. of observations | n = 216 | n = 128 | n = 1527 | n = 790 |
OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | |
Male sex | * | * | 0.8 (0.60–1.05) | * |
Neonate (≤ 1 month) | * | * | * | 0.7 (0.45–1.15) |
Malnutrition | 1.9 (0.95–3.88) | * | 2.1 (1.47–2.90)‡ | 1.6 (0.96–2.55) |
HIV infection | NA | 3.4 (1.22–9.40)† | NA | 2.1 (1.29–3.26)† |
Other underlying infectious disease | * | * | 1.8 (1.13–2.87)† | * |
Underlying non-infectious disease | * | * | * | * |
Malaria | * | * | * | * |
Hospital-acquired infection | * | * | * | * |
Polymicrobial infection | * | * | * | * |
Growth in blood-culture of: | ||||
- Enterobacteriaceae | 3.5 (1.71–7.03)† | 5.6 (2.06–14.95)† | 3.3 (2.09–5.34)‡ | 4.2 (2.27–7.65)‡ |
- Non -Enterobacteriaceae | 2.4 (0.92–6.13) | 4.0 (0.99–16.45) | 2.4 (1.02–5.46)† | 2.7 (0.80–8.81) |
- Candida spp. | 2.6 (0.91–7.29) | 2.9 (0.70–12.09) | 2.5 (1.02–6.03)† | * |
Inappropriate antimicrobial treatment | 2.1 (1.09–4.16)† | 2.3 (0.95–5.58) | 2.1 (1.14–3.93)† | 1.7 (0.76–3.73) |