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Table 5 Logistic regression analysis of risk factors for intra-hospital death from laboratory-confirmed bloodstream infection and clinically suspected systemic infection

From: Antimicrobial resistance predicts death in Tanzanian children with bloodstream infections: a prospective cohort study

Characteristic Laboratory-confirmed bloodstream infection Clinically suspected systemic infection
HIV-status analyzed No Yes No Yes
No. of observations n = 216 n = 128 n = 1527 n = 790
  OR (95%CI) OR (95%CI) OR (95%CI) OR (95%CI)
Male sex * * 0.8 (0.60–1.05) *
Neonate (≤ 1 month) * * * 0.7 (0.45–1.15)
Malnutrition 1.9 (0.95–3.88) * 2.1 (1.47–2.90)‡ 1.6 (0.96–2.55)
HIV infection NA 3.4 (1.22–9.40)† NA 2.1 (1.29–3.26)†
Other underlying infectious disease * * 1.8 (1.13–2.87)† *
Underlying non-infectious disease * * * *
Malaria * * * *
Hospital-acquired infection * * * *
Polymicrobial infection * * * *
Growth in blood-culture of:     
- Enterobacteriaceae 3.5 (1.71–7.03)† 5.6 (2.06–14.95)† 3.3 (2.09–5.34)‡ 4.2 (2.27–7.65)‡
- Non -Enterobacteriaceae 2.4 (0.92–6.13) 4.0 (0.99–16.45) 2.4 (1.02–5.46)† 2.7 (0.80–8.81)
- Candida spp. 2.6 (0.91–7.29) 2.9 (0.70–12.09) 2.5 (1.02–6.03)† *
Inappropriate antimicrobial treatment 2.1 (1.09–4.16)† 2.3 (0.95–5.58) 2.1 (1.14–3.93)† 1.7 (0.76–3.73)
  1. OR, odds ratio; 95%CI, 95% confidence interval. *Variables with P > 0.2 were removed from the models. Statistically significant risk factors are marked † P < 0.05 and ‡ P < 0.001.