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Table 1 Relation between SLC11A1 and IL8R polymorphisms and tuberculosis in Chinese

From: Sex- and age-dependent association of SLC11A1polymorphisms with tuberculosis in Chinese: a case control study

Alleles/genotypes TB patients Control subjects Odds ratio (95% CI) Pvalue
Comparison of allele frequencies
   SLC1 a       
(GT)9 478 (86%) 493 (87%) 1  
Others 78 (14%) 71 (13%) 1.13 (0.80 – 1.60) 0.4780
   SLC6a/b b       
G-TGTG 462 (83%) 497 (88%) 1  
A- ---- 94 (17%) 67 (12%) 1.51 (1.08 – 2.12) 0.0165 c
   IL8rb       
C 370 (67%) 395 (70%) 1  
T 186 (33%) 169 (30%) 1.18 (0.91 – 1.51) 0.2096
Comparison of genotype frequencies
   SLC1 a       
(GT)9/(GT)9 204 (73%) 214 (76%) 1  
(GT)9/others 70   65    
   (27%)   (24%) 1.14 (1.09 – 2.32) 0.4957
others/others 4   3    
   SLC6a/b b       
G-TGTG/G-TGTG 192 (69%) 220 (78%) 1  
G-TGTG/A- ---- 78   57    
   (31%)   (22%) 1.59 (1.09 – 2.32) 0.0163 c
A- ----/A- ---- 8   5    
   IL8rb       
C/C 122 (44%) 135 (48%) 1  
C/T 126   125    
   (56%)   (52%) 1.17 (0.84 – 1.64) 0.3438
T/T 30   22    
  1. a "Others" represent the minor alleles (GT)10 and (GT)11 of the marker SLC1.
  2. b Markers SLC6a and SLC6b are in perfect LD and thus are analyzed as a single marker (SLC6a/b).
  3. c Significant even after correction of multiple testing based on false discovery rate at a level of 0.05. The adjusted cut-off P value is 0.0167 for six comparisons. For details, see additional file 1.