Figure 3

The impact of male circumcision (MC) on HIV prevalence in the Botswana setting, according to our compartmental model, with high, 80%, MC uptake (bottom panel) and moderate, 50%, MC uptake (top panel). Predictions are for the period 2000–2100, when male circumcision is introduced in 2010. In addition the figure shows the results of 4 different sensitivity analyses: RR0.25: if protection afforded by circumcision would be as high 75% (RR 0.25); RR0.60: if it would be as low as 40% (RR 0.60); DISINHIB: if it would lead to disinhibition in the sense that condom use in high risk sex would be abandoned; MF 0.75: if male circumcision would reduce the risk of male-to-female transmission by 25%.