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Table 2 ELISA optical densities with HspX and GlcB recombinant antigens obtained for the different groups investigated.

From: Humoral response to HspX and GlcB to previous and recent infection by Mycobacterium tuberculosis

 

HspX

GlcB

 

IgG m ± sd

IgM m ± sd

IgG m ± sd

IgM m ± sd

Uninfected

0.231 ± 0.110

1.090 ± 0.504

0.975 ± 0.614

0.947 ± 0.263

Previous LTBI

0.223 ± 0.121

0.957 ± 0.510

0.977 ± 0.595

0.942 ± 0.314

Recent LTBI

0.252 ± 0.167

1.519 ± 0.394*

0.816 ± 0.574

1.053 ± 0.338

  1. LTBI = latent tuberculosis infection; m = mean of optical density; sd = standard deviation
  2. *IgM against HspX specific humoral responses is significantly higher for recent LTBI than for uninfected (P < 0.0001), and LTBI (P < 0.0001) individuals. There was no statistical difference between IgG OD against HspX among the different groups. There was no statistical difference between IgG and IgM OD against GlcB.