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Table 2 Frequency of HIV-1 RNA detection in CSF according to the clinical and laboratory characteristics of the patients

From: Factors influencing cerebrospinal fluid and plasma HIV-1 RNA detection rate in patients with and without opportunistic neurological disease during the HAART era

Characteristic

Presence (n)

CSF HIV-1 RNA

p (univariate)b

p (multivariate)c

OR

  

>80 (%)a

<80 (%)

   

Diseased

Yes (71)

63.4

36.6

< 0.001

0.0010

22.1

 

No (19)

26.3

73.7

   

CD4

<200 (17)

64.4

35.6

< 0.001

0.0021

18.7

 

>200 (73)

17.6

82.4

   

ARV use

No (40)

82.5

17.5

< 0.001

NS

*

 

Yes (49)

34.7

65.3

   

Plasma viral load

>80 (56)a

71.4

28.6

< 0.001

0.0008

22.6

 

<80 (14)

14.3

85.7

   
  1. aDetection limit: 80 copies/ml; bchi-square test; cmultivariate logistic regression analysis; dneurological disease; ARV, antiretroviral drug; NS, not significant; OR, odds ratio.
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BMC Infectious Diseases

ISSN: 1471-2334

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