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Table 1 Characteristics of the 90 subjects studied

From: Factors influencing cerebrospinal fluid and plasma HIV-1 RNA detection rate in patients with and without opportunistic neurological disease during the HAART era

Mean age [years (range)]

36 (20–60)

Sex (n)

 

   Male

65

   Female

25

CD4-positive cells (cells/mm3)

 

   Mean

149

   Median

89

   Range

1–405

Mean time since diagnosis [month (range)]

24 (0.5–108)

Pre-existing ARV therapy (n)

 

   Yes

49

   No

40

Mean duration of ARV therapy [month (range)]

10 (0.3–60)

Neurologically asymptomatic (n)

19

Neurologically symptomatic (n)

71

   HIV-associated dementia

6

   Vacuolar myelopathy

1

   Opportunistic CNS infections (43)

 

   Toxoplasmosis

19

   Cryptococcal meningitis

15

   Tuberculosis meningitis

3

   PML

2

   Associations

 

   Cryptococcal and tuberculous

3

   Cryptococcal and toxoplasmosis

1

   Cryptococcal and vacuolar myelopathy

1

Other (stroke, brain abscess, neuropathy)

4

Undetermined neurological diagnosis

16

  1. ARV, antiretroviral drug; CNS, central nervous system;
  2. PML, progressive multifocal leukoencephalopathy