Table 5 Mutational frequencies of levofloxacin, vancomycin, teicoplanin, amikacin, ceftazidime, cefepime, imipenem and piperacillin/tazobactam alone and in triple combinations
Strain | LVX | VA | TEC | AMK | CAZ | FEP | IPM | TZP | Triple combinations* |
|---|---|---|---|---|---|---|---|---|---|
7095 | <10-9 | <10-9 | <10-9 | 4.52 × 10-7 | n.d. | n.d. | n.d. | <10-9 | <10-9 |
7096 | <10-9 | <10-9 | <10-9 | 1.6 × 10-7 | n.d. | n.d. | 1.03 × 10-6 | n.d. | <10-9 |
8957 | 4.9 × 10-5 | <10-9 | <10-9 | <10-9 | n.d. | n.d. | n.d. | n.d. | <10-9 |
7176 | 2.4 × 10-6 | <10-9 | <10-9 | 3.65 × 10-8 | n.d. | n.d. | 8.52 × 10-5 | n.d. | <10-9 |
7171 | <10-9 | <10-9 | <10-9 | 7.57 × 10-7 | n.d. | n.d. | n.d. | n.d. | <10-9 |
2106 | n.d. | <10-9 | <10-9 | <10-9 | n.d. | n.d. | 2.3 × 10-5 | n.d. | <10-9 |
7117 | n.d. | <10-9 | <10-9 | 7.24 × 10-7 | n.d. | n.d. | n.d. | n.d. | <10-9 |
7169 | n.d. | <10-9 | <10-9 | <10-9 | n.d. | n.d. | n.d. | n.d. | <10-9 |
6491 | n.d. | <10-9 | <10-9 | 6 × 10-8 | n.d. | n.d. | n.d. | n.d. | <10-9 |