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Table 4 Multivariate analysis of factors associated with in-hospital mortality

From: Common TNF-α, IL-1β, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome from Gram negative sepsis

 

Model 1

Model 2

Model 3

Variable

RR (95% CI)

P value

RR (95% CI)

P value

RR (95% CI)

P value

Age, per year increment

1.02 (1.00–1.04)

0.026

-

 

1.02 (1.00–1.03)

0.053

Diseases severity

  

-

 

-

 

   Sepsis

1.0

     

   Severe sepsis

1.25 (0.65–2.39)

     

   Septic shock

1.70 (0.48–6.05)

0.674

    

Intensive care admission

  

-

 

-

 

No

1.0

     

Yes

2.50 (0.85–7.42)

0.098

    

Polymicrobial infection

  

-

   

No

1.0

   

1.0

 

Yes

3.02 (1.58–7.41)

0.001

  

2.52 (1.27–5.01)

0.008

Hemoglobin, per μmol/L increase

-

 

0.71 (0.52–0.97)

0.031

0.70 (0.56–0.88)

0.002

Leukocyte count, per 10 9 /mL increase

-

 

1.00 (0.96–1.05)

0.795

-

 

C-reactive protein, per milligram/L increase

-

 

1.00 (0.99–1.00)

0.287

-

 

Urea, per μmol/L increase

-

 

1.02 (0.98–1.06)

0.234

-

 

Alanine transferase, per unit/L increase

-

 

0.99 (0.98–1.00)

0.195

-

 
  1. RR: relative risk; CI: confidence interval