Table 1 Performance of Plasmodium detection tests in endemic populations: a) detection of the presence of parasites, b) diagnosis of a malaria. The parameters considered include the specificity of the test for the detection of parasites in blood (Snp), the corresponding specificity (Spp), the prevalence of malaria infection in the general population (x), and the pre-test probability of a malaria attack in a patient with fever (m)
From: Utility of the detection of Plasmodiumparasites for the diagnosis of malaria in endemic areas
a) Detection of parasites | |||
|---|---|---|---|
Disease status | |||
Malaria | Other febrile illness, parasites present | Other febrile illness, parasites absent | |
Positive parasite detection test | Snp | Snp | 1-Spp |
Negative parasite detection test | 1-Snp | 1-Snp | Spp |
Column totals | 1 | 1 | 1 |
Prevalence of infection in the general population | - | x | 1-x |
b) Detection of malaria (disease) | |||
Malaria | Other febrile illness | ||
Positive parasite detection test | Snp | Snp·x + (1-Spp)·(1-x) | |
Negative parasite detection test | 1-Snp | (1-Snp)·x + Spp·(1-x) | |
Column totals | 1 | 1 | |
Pre-test probability of malaria | m | 1-m | |