Table 2 Comparison of characteristics of patients with TTP in the 1stand 4thquartile.
From: Time to positivity in blood cultures of adults with Streptococcus pneumoniaebacteremia
Characteristic | 1stTTP quartile | 2thand 3rdTTP quartiles | 4thTTP quartile | p* |
|---|---|---|---|---|
Total (n) | 26 | 54 | 25 | |
TTP median (interquartile range) | 8.8 (7.18–10.2) | 12.4 (11.8–13) | 23.94 (14.2–15.5) | |
Basal characteristics | ||||
Age (years) | 68.5 ± 18.4 | 64.6 ± 18.3 | 67.32 ± 17.62 | >0.1 |
Male n (%) | 14 (53.8) | 33 (61.1) | 14 (56) | >0.1 |
Time evolution (days) | 3.6 ± 2.8 | 3.4 ± 3.3 | 3.7 ± 3.4 | >0.1 |
Hospitalized n (%) | 26 (100) | 46 (88.5) | 20 (80) | 0.02 |
Previous antibiotic n (%) | 3 (11.5) | 4 (7.4) | 2 (8) | >0.1 |
Comorbidities | ||||
Alcoholism n (%) | 1 (3.8) | 11 (20.4) | 5 (20) | >0.1 |
COPD n (%) | 6 (23.1) | 12 (22.2) | 13 (52) | 0.03 |
Diabetes n (%) | 2 (7.7) | 8 (14.8) | 1 (4.0) | >0.1 |
Neoplasm n (%) | 0 | 3 (5.6) | 2 (8) | >0.1 |
Immunosuppression n (%) | 2 (7.7) | 2 (3.7) | 1 (4) | >0.1 |
Dementia n (%) | 1 (3.8) | 3 (5.6) | 2 (8) | >0.1 |
Clinical presentation | ||||
Ta(°C) | 38.3 ± 0.7 | 37.9 ± 1 | 37.8 ± 0.8 | >0.1 |
Chills n (%) | 7 (26.9) | 18 (33.3) | 9 (36) | >0.1 |
Confusion n (%) | 9 (34.6) | 6 (11.1) | 4 (16) | 0.08 |
Severe sepsis or shock n (%) | 5 (19.2) | 6 (11.1) | 1 (4) | 0.09 |
Bilateral pneumonia n (%) | 3 (11.5) | 5 (9.3) | 5 (20) | >0.1 |
Origin of bacteremia | ||||
Meningitis n (%) | 7 (26.9) | 0 | 0 | <0.001 |
Pneumonia n (%) | 17 (65.4) | 45 (79.6) | 23 (92) | 0.02 |
Others n (%) | 2 (7.7) | 8 (14.8) | 3 (12) | >0.1 |
Laboratory parameters | ||||
Penicillin susceptible n (%) | 21 (80.8) | 45 (83.3) | 19 (76) | >0.1 |
WBC (cells/μL) | 15880 ± 5120 | 19070 ± 12926 | 19633 ± 10812 | 0.01 |
Neutrophils (%) | 89.7 ± 6.06 | 78.6 ± 15.8 | 85.4 ± 10.2 | 0.06 |
Platelets (cells/μL) | 211580 ± 64385 | 188340 ± 76700 | 234000 ± 116387 | 0.03 |
Creatinine level (mg/dL) | 1.3 ± 0.6 | 1.1 ± 0.5 | 1.3 ± 1 | >0.1 |
Albumin (mg/dL) | 2.8 ± 0.7 | 3 ± 0.6 | 3 ± 0.6 | >0.1 |
Cholesterol (mg/dL) | 131 ± 56.5 | 139.6 ± 57.7 | 177 ± 53.3 | >0.1 |
Positive blood cultures (n) | 5 ± 1.56 | 4 ± 2 | 2 ± 1.4 | <0.001 |
Outcome | ||||
Hospital stay (days) | 17.3 ± 12.8 | 23.64 ± 71.6 | 11.4 ± 7.9 | 0.07 |
Exitus n (%) | 4 (15.4) | 5 (9.3) | 4 (16) | >0.1 |
ICU n (%) | 9 (34.6) | 5 (9.3) | 0 | <0.001 |