Figure 1

CSF and blood bacterial concentration during experimental pneumococcal meningitis. *Significant difference between groups (Kruskal Wallis test, P < 0.05). There was a significant higher blood bacterial concentration in bacteraemic rabbits (n = 9) than in controls (n = 9) at 2–6 and 12 hours and than in immunized rabbits (n = 8) at 2–16 hours, respectively, and higher in controls than in immunized rabbits at 10–16 hours (Mann Whitney test, P < 0.017). All data are shown as medians (25–75 percentiles).