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Figure 2 | BMC Infectious Diseases

Figure 2

From: Differential activation of inflammatory pathways in A549 type II pneumocytes by Streptococcus pneumoniae strains with different adherence properties

Figure 2

High-binders induce prolonged degradation of IκB compared to low-binders. All values are mean ± one standard deviation, based on three independent experiments. 2A. IκB degradation induced by serotype 3 evolved high-binder and 3 low-binding parent strains. Closed squares, IκB level relative to time zero in A549 treated with low-binder. Open triangles, IκB level relative to time zero in A549 treated with high-binder. Representative Western blots for IκB are shown below each line graph. 2B. IκB degradation induced by serotype 9N low-binding clinical isolate and serotype 6B high-binding clinical isolate. Closed squares, IκB level relative to time zero in A549 treated with low-binder. Open triangles, IκB level relative to time zero in A549 treated with high-binder. Representative Western blots for IκB shown below line graph.

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